I like succinate dehydrogenase (pronounced suck SIN ate  dee hi DROJ in aze).  Despite its intimidating name to a non-biochemist, it has a wonderful message.  If you are a creationist, you should like it, too. You see, there is no rational explanation for its existence apart from God’s decision to design it and use it.

Succinate dehydrogenase (SD) is an enzyme. It is extremely ubiquitous. Almost all living organisms use it, including all of the various kinds of plants, animals, fungi, and aerobic bacteria.  Beyond this, many anaerobic bacteria also use it. Yet, it is one of the most complex enzymes in existence. It is comprised of over 1,100 amino acids.  Whether it is being used by a bacterium, an apricot tree, or a man makes no difference. In every place that it appears, over 1,100 amino acids are used to make it.

There are 20 amino acid possibilities for each of these 1,100-plus amino acids.  In an enzyme, the choice of amino acids at some locations is not very critical, while at others there is no freedom of choice possible—changing only one amino acid at a critical location can render an enzyme completely ineffective.  Suppose one allows 2 possible choices at each of the amino acid locations of SD, a reasonable generalized approximation.  If one then goes through the calculations, the odds against getting succinate dehydrogenase in a single step are approximately 101100 (see endnote). Considering that there are only an estimated 1080 atoms in the known, observable universe,1 even evolutionists will acknowledge that these odds are much, much too large for SD to have appeared in a single step….

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