Heavy metal rock star Ozzie Osbourne, recently had his entire genome sequenced. He said that he was curious if his genome was the reason he was still alive after a lifetime of alcohol and drug abuse. Knome, the company that analyzed Ozzy’s full genome, disclosed that they found a sequence on one of his chromosomes that appears to be from a Neandertal ancestor. Knome founder, George Church said that he has three to four times as much Neandertal DNA than Ozzie has:
What genetic oddities does rock’s Prince of Darkness and beheader of bats have entangled deep in his genetic code? Knome, the company that analyzed Ozzy’s full genome, divulges some of the details in a Q&A….
Were there any big surprises hiding in his genome?
Pearson: For a long time we thought that Neandertals didn’t have any descendents today, but it turns out that Asians and Europeans have some evidence of Neandertal lineage—like a drop in the bucket. We found a little segment on Ozzy’s chromosome 10 that very likely traces back to a Neandertal forebearer.
Ozzy, of course, was tickled to hear this. But Knome founder George Church’s genome has about three times as much Neandertal, which we thought was funny….
This follows the report from Knome back in May, when they revealed that everyone that lives outside of Africa contains 1% – 4% Neandertal DNA:
Researchers sequencing Neandertal DNA have concluded that between 1 and 4 percent of the DNA of people today who live outside Africa came from Neandertals, the result of interbreeding between Neandertals and early modern humans.
A team of scientists led by Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology in Leipzig pieced together the first draft of the sequence—which represents about 60 percent of the entire genome—using DNA obtained from three Neandertal bones that come from Vindija cave in Croatia and are more than 38,000 years old. The researchers detail their analysis of the sequence in the May 7 Science….