If anyone really wants to see just how complex our bodies are, they need to look down to the molecular structures that keep us living. From molecules with legs that walk to complex sugars with a language all their own, the molecular workings of the human body are more complicated than they workings of any factory.
One such group of molecular machines are membrane bound proteins knows as G Protein-Coupled Receptors also known as GPCRs. These receptors transverse both layers of the cell membrane, creating a highly regulated molecular portal. They function in regulating the intake of certain other molecules and chemicals such as molecules that we perceive as odors, certain hormones, neurotransmitters and even light.
Once the GPCR identifies the right molecule, they will bind to it and then carefully fold in such a way where the target molecule is brought into the cell where it is then released. They don’t just bind to any molecule that comes their way. Different GPCRs target different molecules. Researchers in the medical field have been working on finding the right drugs and medicines to target specific GPCRs. Some estimates indicate that nearly 40% of all medicinal drugs utilize GPSRs for their delivery to specific cells. Many cancer drugs are made specifically to be recognized by GPCRs.
GPCRs consist of seven folds that span both the inner and outer cell membranes. The internal end of the protein has receptors that detect what compounds the cell needs. Once it identifies what the cell needs, a signal is sent to the opposite end of the protein that remains outside the cell. The external end of the protein that remains outside the cell membrane also has receptors that search for the right things to bring into the cell.
Researchers have known of the GPCR receptors for some time and have been creating drugs and medicines to target them. However, it has been difficult for researchers to get a detailed view of them to learn more about their structure and design. Whenever they have tried to remove a GPCR complex from cell to study, it readily breaks apart as they are extremely fragile.
After nearly 20 years of research and 15 or so different breakthroughs that are all dependent on each other, scientists have finally been able to coax a GPCR into crystalline form. The importance of this is that it allows them to actually see and study the structure and design of the protein. Most people are not aware that when Watson and Crick first identified the double helical structure of DNA that they did it by studying the crystalline form of the molecule.
What intrigues me about this study is one the complexity of the GPCRs and how well they are designed to function in specific ways. Additionally, think about the years and hundreds of millions of dollars that have been spent studying a molecular structure that evolutionists believe formed by random chance. Better yet, it didn’t form just once by random chance, but it did so a number of times since there are a number of different types of GPCRs.
When I study the human body down to the molecular level, I see such exquisite and complex detail that screams loudly the name of our Creator God. It also reminds me of Psalm 139:13-14 which declares:
For you formed my inward parts; you knitted me together in my mother’s womb. I praise you, for I am fearfully and wonderfully made. Wonderful are your works; my soul knows it very well.
Large, Medically Important Class of Proteins Starts to Yield Its Secrets, Science Daily, July 12, 2012.
It is with great sadness that we have watched the events surrounding the starvation-induced death of Terry Schiavo. At no time in modern history has it been more obvious that the salt once prevalent in American society has lost its saltiness. Basic understanding of the Scriptures and deference to the authority of Gods holy Word no longer guide the decision-making processes behind modern courts and communities, or even many Christian churches and homes.
This compelling, illustrated lecture was presented by anatomist Dr. David Menton at Answers in Genesis’ Defending the Faith conference in Ft. Lauderdale, Florida. You have never seen a presentation regarding the value and dignity of human life that is as powerful, and as respectful as this.
Dr. Menton explains that the question is not when does life begin, but when does a person begin? He explains from anatomical science and biology the truth of Psalm 139:13-16 where God says that He weaves us together in the womb. The DVD also illustrates the amazing and intricate design of the womb and the processes of fertilization, implantation, embryonic development and birth itself. Dr. Menton reveals that each of these is a series of miracles (irreducible complexities) that cannot be explained by chance and random processes. Even more important, as Dr. Menton explains with grace and sensitivity in the wrap-up of the video, is the second birth process of salvation explained in John 3.